Near-infrared fluorescent probe labels Aβ plaques through in vivo bioorthogonal reactions
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Near-infrared fluorescent probes are increasingly being explored as markers for Amyloid-beta (Aβ) plaques, playing a crucial role in the early detection of Alzheimer’s disease. In this study, we aim to engineer a probe that leverages bioorthogonal reactions, enabling the activation or deactivation of fluorescence through light modulation. 💡